Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 18/20 | 0.89 |
| ▸ | CDK2 | P24941 | 18/20 | 0.89 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398263 | 0.91 | CDK5 (0.72) | CCNA2CDK2CDK5CDK5R1MEN1 | |
| SCHEMBL4393547 | 0.90 | CCNA2 (0.71) | CCNA2CDK2CCNE1CDK5CDK5R1 | |
| SCHEMBL5725190 | 0.90 | CCNA2 (0.91) | CCNA2CDK2CCNE1CDK5CDK5R1 | |
| SCHEMBL20142073 | 0.86 | CCNA2 (0.68) | CCNA2CDK2CDK5CDK5R1MEN1 | |
| SCHEMBL20142288 | 0.86 | CCNA2 (0.83) | CCNA2CDK2CCNE1 | |
| SCHEMBL20142148 | 0.85 | GSK3A (0.73) | CCNA2CDK2CDK5CDK5R1MEN1 | |
| SCHEMBL13633763 | 0.85 | CDK5 (0.65) | CCNA2CDK2CDK5CDK5R1MEN1 | |
| SCHEMBL20142403 | 0.85 | CCNA2 (0.78) | CCNA2CDK2CDK5CDK5R1MEN1 | |
| SCHEMBL20142846 | 0.85 | CCNA2 (0.78) | CCNA2CDK2CDK5CDK5R1MEN1 | |
| SCHEMBL4395265 | 0.85 | GSK3A (0.73) | CCNA2CDK2CDK5CDK5R1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |