Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129613 | 0.80 | PLD1 (0.54) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| SCHEMBL20129603 | 0.80 | PLD1 (0.54) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| SCHEMBL30531432 | 0.80 | PLD1 (0.54) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| SCHEMBL20141500 | 0.80 | PLD1 (0.54) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| Hydrochloric Acid SCHEMBL20141813 | 0.79 | PLD1 (0.53) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| Hydrochloric Acid SCHEMBL20141815 | 0.79 | PLD1 (0.53) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| SCHEMBL21360312 | 0.78 | SLC6A2 (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL18291384 | 0.77 | HTR2C (0.44) | HTR2CHTR2AHTR2BPIM1PIM3 | |
| SCHEMBL31310154 | 0.76 | CHRM4 (0.44) | ADAMTS5 | |
| SCHEMBL18291427 | 0.76 | HTR2C (0.41) | HTR2CHTR2AHTR2BPIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |