Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.41 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388194 | 0.83 | AR (0.62) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL7524105 | 0.83 | AR (0.62) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL7528396 | 0.83 | AR (0.62) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL1660394 | 0.83 | AR (0.62) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL1871089 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL573134 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL829177 | 0.81 | AR (0.65) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL1878340 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EKEAP1ARL3MBTL1 | |
| SCHEMBL31316614 | 0.80 | MC4R (0.42) | ALDH1A1KDM4EMAPTHRH3 | |
| SCHEMBL2783770 | 0.80 | GAA (0.44) | ALDH1A1KDM4EMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |