Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142502 | 0.90 | MEN1 (0.64) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142426 | 0.89 | MEN1 (0.63) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142179 | 0.89 | GSK3A (0.53) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142852 | 0.88 | MEN1 (0.56) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142185 | 0.87 | CDK5 (0.60) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142461 | 0.86 | MEN1 (0.59) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL4393604 | 0.84 | MEN1 (0.88) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL4395515 | 0.84 | MEN1 (0.88) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142844 | 0.81 | MAPT (0.57) | MEN1KMT2ANPC1CDK5CDK5R1 | |
| SCHEMBL20142452 | 0.79 | NPC1 (0.50) | MEN1KMT2ANPC1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |