Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.58 |
| ▸ | RPTOR | Q8N122 | 9/20 | 0.58 |
| ▸ | MLST8 | Q9BVC4 | 9/20 | 0.58 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | GPR6 | P46095 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133570 | 0.88 | MTOR (0.61) | MTORRPTORMLST8GRM1HCRTR1 | |
| SCHEMBL20142908 | 0.88 | MTOR (0.61) | MTORRPTORMLST8GRM1HCRTR1 | |
| SCHEMBL20133591 | 0.88 | MTOR (0.57) | MTORRPTORMLST8GRM1HCRTR1 | |
| SCHEMBL20149878 | 0.88 | MTOR (0.57) | MTORRPTORMLST8GRM1HCRTR1 | |
| SCHEMBL20149921 | 0.84 | MTOR (0.65) | MTORRPTORMLST8MAPT | |
| SCHEMBL20149762 | 0.84 | MTOR (0.55) | MTORRPTORMLST8GRM1HCRTR1 | |
| SCHEMBL20149916 | 0.83 | MTOR (0.52) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20133587 | 0.83 | MTOR (0.52) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20149914 | 0.83 | MTOR (0.52) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL22693219 | 0.82 | MTOR (0.54) | MTORRPTORMLST8GRM1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |