SCHEMBL2014295

SCHEMBL2014295

O=C(c1ccccc1)c1ccc2ccccc2c1.O=C(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.58
MCL1 Q07820 1/20 0.58
BAD Q92934 1/20 0.58
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
CDC25B P30305 1/20 0.54
CLK1 P49759 1/20 0.53
DYRK1A Q13627 1/20 0.53
DYRK1B Q9Y463 1/20 0.53
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
NR4A1 P22736 1/20 0.51
NR4A2 P43354 1/20 0.51
NR4A3 Q92570 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9856895 0.94 CDC25B (0.56) BCL2MCL1BADMEN1KMT2A
Naphthalene SCHEMBL11467392 0.88 CDC25B (0.67) BCL2MCL1BADMEN1KMT2A
SCHEMBL29522736 0.87 CDC25B (0.69) BCL2MCL1BADMEN1KMT2A
SCHEMBL547632 0.87 CDC25B (0.69) BCL2MCL1BADMEN1KMT2A
SCHEMBL29834246 0.85 MEN1 (0.75) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL124894 0.85 MEN1 (0.75) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL27656847 0.82 ALDH1A1 (0.59) BCL2MCL1BADMEN1KMT2A
Benzil SCHEMBL10791220 0.82 CDC25B (0.62) BCL2MCL1BADMEN1KMT2A
SCHEMBL7189887 0.82 CDC25B (0.68) BCL2MCL1BADMEN1KMT2A
SCHEMBL28211179 0.82 ALDH1A1 (0.66) MEN1KMT2ANPC1RAB9ACLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3596192-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE SLURRIES The Procter and Gamble Company (US) 2020-01-22 EP disclosed
WO-2018169531-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE SLURRIES THE PROCTER & GAMBLE COMPANY (US) 2018-09-20 WO disclosed
WO-2017158497-A1 HYDROPHOBICALLY MODIFIED UREA ETHERS AS STRUCTURANTS FOR HYDROPHOBIC SYSTEMS PROCTER & GAMBLE INERNATIONAL OPERATIONS SA (CH) 2017-09-21 WO disclosed
EP-2512406-A1 PERFUMES AND PERFUME ENCAPSULATES The Procter & Gamble Company (US) 2012-10-24 EP disclosed
EP-2513280-A1 COMPOSITION COMPRISING ENCAPSULATES, AND PROCESS FOR MAKING THEM The Procter & Gamble Company (US) 2012-10-24 EP disclosed
WO-2011075551-A1 PERFUMES AND PERFUME ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2011-06-23 WO disclosed
WO-2011075556-A1 COMPOSITION COMPRISING ENCAPSULATES, AND PROCESS FOR MAKING THEM THE PROCTER & GAMBLE COMPANY (US) 2011-06-23 WO disclosed