Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044282 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL3231146 | 0.95 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL7278054 | 0.95 | NR1I2 (0.53) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL15664773 | 0.95 | NR1I2 (0.53) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL27522848 | 0.94 | BCHE (0.51) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| Hydrochloric Acid SCHEMBL27415879 | 0.93 | NR1I2 (0.52) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| Acetic Acid SCHEMBL27390252 | 0.90 | NR1I2 (0.50) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL8958766 | 0.90 | BCHE (0.54) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL1825154 | 0.90 | BCHE (0.54) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL3969870 | 0.90 | LMNA (0.52) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968589-B2 | Method of treating disease by auricular anesthesia of cranial nerves | CREWS THOMAS M (US) | 2018-05-15 | — | — | US | disclosed |