Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948779 | 1.00 | HRH3 (0.40) | HRH3SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL26767784 | 0.98 | HRH3 (0.42) | HRH3SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL12698815 | 0.98 | HRH3 (0.42) | HRH3SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL2230356 | 0.93 | HRH3 (0.36) | HRH3SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL4267683 | 0.91 | HRH3 (0.38) | HRH3SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL27942598 | 0.91 | FDPS (0.36) | HRH3MAPTL3MBTL1MAPK1NPSR1 | |
| SCHEMBL4275008 | 0.91 | FDPS (0.36) | HRH3MAPTL3MBTL1MAPK1NPSR1 | |
| SCHEMBL4276675 | 0.91 | FDPS (0.36) | HRH3MAPTL3MBTL1MAPK1NPSR1 | |
| SCHEMBL2228961 | 0.91 | FDPS (0.36) | HRH3MAPTL3MBTL1MAPK1NPSR1 | |
| SCHEMBL4275497 | 0.90 | HRH3 (0.37) | HRH3ALDH1A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968554-B2 | Modified drugs for use in liposomal nanoparticles | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2018-05-15 | — | — | US | disclosed |