Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13010067 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL18680910 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL41360 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13559221 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL16258664 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL18537398 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL3794703 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13061814 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL31662742 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Hydrogen Sulfide SCHEMBL28283740 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968628-B2 | Methods and compositions for treating flaviviruses and pestiviruses | IDENIX PHARMACEUTICALS LLC (US) | 2018-05-15 | — | — | US | disclosed |