SCHEMBL41360

SCHEMBL41360

C[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 3/20 0.55
PI4K2B Q8TCG2 3/20 0.55
PI4K2A Q9BTU6 3/20 0.55
PI4KB Q9UBF8 3/20 0.55
ADORA2A P29274 3/20 0.55
ADORA3 P0DMS8 5/20 0.53
SLC28A1 O00337 2/20 0.53
DPP4 P27487 1/20 0.53
MEN1 O00255 1/20 0.53
MAP3K7 O43318 1/20 0.53
SLC28A2 O43868 1/20 0.53
GAPDH P04406 1/20 0.53
MAPK1 P28482 1/20 0.53
ADORA2B P29275 1/20 0.53
ADORA1 P30542 1/20 0.53
STAT6 P42226 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
DOT1L Q8TEK3 1/20 0.53
SLC29A1 Q99808 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13010067 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL18680910 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL20143496 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL13559221 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL16258664 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL18537398 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL3794703 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL13061814 1.00 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL31662742 0.99 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBADORA2A
Hydrogen Sulfide SCHEMBL28283740 0.99 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4015 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739794-A1 METHODS, COMPOSITONS, AND SYSTEMS FOR ANALYTE DETECTION Stellaromics, Inc. (US) 2026-05-13 EP claimed
EP-4684016-A2 METHODS AND MATERIALS FOR TREATING CANCER The Regents of the University of California (US) 2026-01-28 EP claimed
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN claimed
CN-119836290-A Combination therapy for the treatment of cancer using PRMT5 inhibitors and BCL-2 family inhibitors 米拉蒂治疗公司 2025-04-15 CN claimed
WO-2025036956-A1 NON-SYSTEMIC MRNA ADMINISTRATION ETHRIS GMBH (DE) 2025-02-20 WO claimed
CN-119432957-A Method for preparing RNA by in vitro transcription and application thereof 启辰生生物科技(珠海)有限公司 2025-02-14 CN claimed
WO-2025014828-A1 METHODS, COMPOSITONS, AND SYSTEMS FOR ANALYTE DETECTION STELLAROMICS, INC. (US) 2025-01-16 WO claimed
EP-3825400-B1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF TRANSLATE BIO INC (US) 2024-12-25 EP claimed
EP-4008334-B1 MANNOSE-BASED MRNA TARGETED DELIVERY SYSTEM AND USE THEREOF SHENZHEN RHEGEN BIOTECHNOLOGY CO LTD (CN) 2024-12-04 EP claimed
WO-2024218766-A1 DECOY RNA OLIGONUCLEOTIDES FOR INHIBITING YTHDF2 CATCHME THERAPEUTICS LTD. (IL) 2024-10-24 WO claimed
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 WO claimed
WO-2004050899-A2 METHOD FOR IN VITRO SELECTION OF 2’-SUBSTITUTED NUCLEIC ACIDS ARCHEMIX CORPORATION (US) 2004-06-17 WO claimed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 WO claimed
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-26 US claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 WO claimed
EP-1165585-A1 CLEAVAGE OF NUCLEIC ACID FROM SOLID SUPPORTS Goldsborough, Andrew (FR) 2002-01-02 EP claimed
WO-2000058329-A1 CLEAVAGE OF NUCLEIC ACID FROM SOLID SUPPORTS GOLDSBOROUGH, ANDREW (FR) 2000-10-05 WO claimed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP claimed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO claimed
EP-0526866-A1 The use of adenosine compounds for the preparation in the treatment of ischaemia BIORESEARCH S.p.A. (IT) 1993-02-10 EP claimed