Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486444 | 0.90 | TSHR (0.45) | KMT2ARAB9AALDH1A1MEN1TSHR | |
| SCHEMBL7677497 | 0.85 | KMT2A (0.53) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL27627519 | 0.85 | KMT2A (0.53) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL8235210 | 0.85 | KMT2A (0.53) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL11028996 | 0.85 | TSHR (0.44) | KMT2AMEN1TSHRBACE1HDAC8 | |
| Hydrochloric Acid SCHEMBL10755389 | 0.84 | MEN1 (0.55) | KMT2AALDH1A1MEN1TSHRBACE1 | |
| SCHEMBL7225047 | 0.80 | ACE (0.47) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL7225043 | 0.80 | ACE (0.47) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL22801020 | 0.80 | TDP1 (0.57) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| Cadaverine Tartrate SCHEMBL7432649 | 0.79 | MEN1 (0.47) | KMT2AMEN1TSHRBACE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969709-B2 | Guanidinobenzoic acid ester compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-15 | — | — | US | disclosed |