Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235210 | 0.86 | KMT2A (0.53) | TSHRBACE1MEN1KMT2AFABP7 | |
| SCHEMBL7677497 | 0.86 | KMT2A (0.53) | TSHRBACE1MEN1KMT2AFABP7 | |
| SCHEMBL27627519 | 0.86 | KMT2A (0.53) | TSHRBACE1MEN1KMT2AFABP7 | |
| Hydrochloric Acid SCHEMBL10755389 | 0.85 | MEN1 (0.55) | TSHRBACE1HDAC8MEN1KMT2A | |
| SCHEMBL20143631 | 0.85 | LMNA (0.47) | TSHRBACE1HDAC8MEN1KMT2A | |
| SCHEMBL17486444 | 0.84 | TSHR (0.45) | TSHRBACE1HDAC8MEN1KMT2A | |
| SCHEMBL7428360 | 0.83 | TSHR (0.45) | TSHRBACE1FABP7FABP5GLA | |
| SCHEMBL11024331 | 0.83 | KDM4E (0.46) | HDAC8MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7225043 | 0.81 | ACE (0.47) | TSHRBACE1MEN1KMT2A | |
| SCHEMBL7225047 | 0.81 | ACE (0.47) | TSHRBACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088350-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0088350-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |