Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16297846 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL2651357 | 0.84 | — | — | |
| SCHEMBL21064667 | 0.77 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL4685007 | 0.77 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL20169222 | 0.74 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL14403837 | 0.72 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL12972991 | 0.71 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL253271 | 0.70 | — | — | |
| SCHEMBL12827125 | 0.70 | CA12 (0.41) | L3MBTL1ALDH1A1LMNACA12CA1 | |
| SCHEMBL14348162 | 0.70 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969770-B2 | Proline compounds as Granzyme B inhibitors | VIDA THERAPEUTICS INC. (CA) | 2018-05-15 | — | — | US | disclosed |