Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906930 | 0.81 | PDK2 (0.40) | PDK2ATMTHRBTDP1KDM4E | |
| SCHEMBL28349427 | 0.81 | PDK2 (0.34) | PDK2ATMCDC25B | |
| SCHEMBL24757959 | 0.78 | PDK2 (0.38) | PDK2ATM | |
| SCHEMBL26604189 | 0.78 | PDK2 (0.33) | PDK2ATM | |
| SCHEMBL24757960 | 0.78 | PDK2 (0.38) | PDK2ATM | |
| SCHEMBL22870182 | 0.78 | ATM (0.37) | PDK2ATMTHRBTDP1MEN1 | |
| SCHEMBL28199301 | 0.77 | PDK2 (0.40) | PDK2ATMTHRBTDP1MEN1 | |
| SCHEMBL14770886 | 0.76 | PDK2 (0.47) | PDK2TDP1MEN1KMT2ALMNA | |
| SCHEMBL20143949 | 0.76 | HTR2A (0.55) | — | |
| SCHEMBL23315086 | 0.75 | CYP2D6 (0.35) | PDK2THRBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230194989-A1 | ETHYNYL DERIVED COMPOSITE, A COMPOSITION COMPRISING THEREOF, A METHOD FOR MANUFACTURING A COATING BY IT, AND A METHOD FOR MANUFACTURING A DEVICE COMPRISING THE COATING | MERCK PATENT GMBH (DE) | 2023-06-22 | — | — | US | disclosed |
| US-10312074-B2 | Method of producing layer structure, layer structure, and method of forming patterns | SAMSUNG SDI CO., LTD. (KR) | 2019-06-04 | — | — | US | disclosed |
| US-9971243-B2 | Polymer, organic layer composition, organic layer, and method of forming patterns | SAMSUNG SDI CO., LTD. (KR) | 2018-05-15 | — | — | US | disclosed |