Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143932 | 0.81 | PDK2 (0.39) | PDK2THRBTDP1ESR1ESR2 | |
| SCHEMBL12520339 | 0.79 | PDK2 (0.41) | PDK2THRBTDP1ESR1ESR2 | |
| SCHEMBL19976611 | 0.75 | UGT2B7 (0.41) | PDK2ATMALDH1A1 | |
| SCHEMBL22870182 | 0.74 | ATM (0.37) | PDK2THRBTDP1ATMRAB9A | |
| SCHEMBL7821184 | 0.71 | APEX1 (0.46) | PDK2THRBTDP1ATMAPEX1 | |
| SCHEMBL23315086 | 0.71 | CYP2D6 (0.35) | PDK2THRBTDP1RAB9AAPEX1 | |
| SCHEMBL2239449 | 0.70 | PDK2 (0.52) | PDK2THRBTDP1ESR1ESR2 | |
| SCHEMBL30341830 | 0.70 | PDK2 (0.52) | PDK2THRBTDP1ESR1ESR2 | |
| SCHEMBL23936830 | 0.70 | PDK2 (0.52) | PDK2THRBTDP1ESR1ESR2 | |
| SCHEMBL19976612 | 0.70 | TYMS (0.53) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170153548-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-01 | — | — | US | disclosed |