Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18636433 | 1.00 | BACE1 (0.34) | BACE1BACE2TNK2RIPK1TAAR1 | |
| SCHEMBL10120795 | 0.91 | TNK2 (0.33) | TNK2TMPRSS2 | |
| SCHEMBL10120799 | 0.91 | TMPRSS2 (0.36) | TNK2RIPK1TMPRSS2 | |
| SCHEMBL12835932 | 0.90 | BACE1 (0.32) | BACE1BACE2CTSLCTSBCTSK | |
| SCHEMBL10082720 | 0.90 | BACE1 (0.34) | BACE1BACE2TNK2RIPK1TAAR1 | |
| SCHEMBL18636432 | 0.89 | TMPRSS2 (0.36) | BACE1BACE2TNK2RIPK1TAAR1 | |
| SCHEMBL12243225 | 0.89 | NPC1 (0.35) | TNK2RIPK1TMPRSS2 | |
| SCHEMBL23823026 | 0.85 | TNK2 (0.34) | BACE1BACE2TNK2RIPK1TAAR1 | |
| SCHEMBL12243148 | 0.85 | TNK2 (0.34) | BACE1BACE2TNK2RIPK1TAAR1 | |
| SCHEMBL17712276 | 0.82 | PDE2A (0.35) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212175-B1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES INC (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-3212174-B1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2018-05-16 | — | — | EP | disclosed |