SCHEMBL20144281

SCHEMBL20144281

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)c1cc([N+](=O)[O-])[nH]n1)NCc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
PCNA P12004 1/20 0.36
TRPV1 Q8NER1 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAOB P27338 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15298154 0.92 HPGD (0.40) HPGDPCNAMEN1KMT2ACNR2
SCHEMBL1754953 0.83 HPGD (0.46) HPGDMEN1KMT2AALDH1A1POLB
SCHEMBL14948193 0.81 HPGD (0.42) HPGDPOLB
SCHEMBL15298144 0.79 HPGD (0.50) HPGDCNR2ALDH1A1
SCHEMBL13248194 0.79 HPGD (0.41) HPGDCNR2POLB
SCHEMBL13248187 0.79 HPGD (0.52) HPGDMEN1KMT2APOLBHTT
SCHEMBL13248184 0.77 HPGD (0.50) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13248185 0.77 HPGD (0.50) HPGDMEN1KMT2APOLBHTT
SCHEMBL16077518 0.74 HPGD (0.54) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL1754975 0.74 HPGD (0.43) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3764084-A1 DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY Ventana Medical Systems, Inc. (US) 2021-01-13 EP disclosed
EP-3764083-A1 DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY Ventana Medical Systems, Inc. (US) 2021-01-13 EP disclosed
EP-2831587-B1 SIGNALING CONJUGATES AND METHODS OF USE VENTANA MED SYST INC (US) 2018-05-16 EP disclosed