SCHEMBL20144547

SCHEMBL20144547

CCCCNC(=O)C(C)(C)CC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.48
ACHE P22303 8/20 0.42
MMP2 P08253 1/20 0.42
CNR1 P21554 1/20 0.42
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22507094 0.94 EPHX1 (0.56) EPHX1CNR1
SCHEMBL22174982 0.90 CASP2 (0.47) EPHX1CNR1
SCHEMBL22992626 0.88 EPHX1 (0.48) EPHX1ACHEMMP2CNR1TSHR
SCHEMBL21946461 0.88 KDM4C (0.42) EPHX1MMP2CNR1
SCHEMBL21696330 0.85 EPHX1 (0.46) EPHX1ACHEMMP2CNR1TSHR
SCHEMBL5021617 0.83 EPHX1 (0.52) EPHX1ACHEMMP2CNR1
SCHEMBL24146674 0.82 PAOX (0.42) EPHX1CNR1
SCHEMBL618269 0.82 EPHX1 (0.50) EPHX1ACHEMMP2CNR1
SCHEMBL23340781 0.81 POLB (0.41) EPHX1
SCHEMBL22175044 0.81 POLB (0.36) EPHX1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3321279-B1 EXENATIDE MODIFIER AND USE THEREOF BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) 2020-02-12 EP disclosed
EP-3321279-A1 EXENATIDE MODIFIER AND USE THEREOF Bright Gene Bio-Medical Technology Co., Ltd. (CN) 2018-05-16 EP disclosed