Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870939 | 0.82 | TDP1 (0.48) | TDP1ALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL11904537 | 0.81 | TDP1 (0.61) | TDP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL38726 | 0.81 | TDP1 (0.61) | TDP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL18911022 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL1660549 | 0.78 | HTT (0.60) | TDP1ALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL16775004 | 0.78 | TDP1 (0.45) | TDP1ALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL23727166 | 0.78 | TDP1 (0.58) | TDP1ALDH1A1HPGDKMT2AKDM4E | |
| Bromide SCHEMBL20513084 | 0.78 | TDP1 (0.58) | TDP1ALDH1A1HPGDKMT2AKDM4E | |
| Fluoride SCHEMBL20513066 | 0.78 | TDP1 (0.58) | TDP1ALDH1A1HPGDKMT2APOLB | |
| Fluoride SCHEMBL21331933 | 0.78 | TDP1 (0.58) | TDP1ALDH1A1HPGDKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321260-B1 | COMPOSITION OBTAINED BY PURIFYING CRUDE FURAN 2,5-DICARBOXYLIC ACID BY HYDROGENATION | EASTMAN CHEM CO (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-3321260-A1 | COMPOSITION OBTAINED BY PURIFYING CRUDE FURAN 2,5-DICARBOXYLIC ACID BY HYDROGENATION | Eastman Chemical Company (US) | 2018-05-16 | — | — | EP | disclosed |