Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 11/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144713 | 0.90 | HRH3 (0.43) | ALDH1A1KMT2AMEN1BRD4ATAD2 | |
| SCHEMBL4422995 | 0.89 | BRD4 (0.42) | GAAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15037972 | 0.85 | MAPT (0.42) | GAAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15038014 | 0.82 | KDM1A (0.42) | GAAALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL13907128 | 0.81 | ALOX15 (0.44) | GAAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15037982 | 0.81 | HRH3 (0.47) | ALDH1A1MAPK1BRD4ATAD2LMNA | |
| SCHEMBL15037988 | 0.80 | HRH3 (0.48) | ALDH1A1KMT2AMEN1BRD4ATAD2 | |
| SCHEMBL15037980 | 0.80 | KDM1A (0.43) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL2676068 | 0.79 | GAA (0.43) | GAAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15037989 | 0.79 | HRH3 (0.50) | ALDH1A1KMT2AMEN1BRD4ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791116-B1 | COUPLER WITH 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINE STRUCTURE, DYEING COMPOSITION COMPRISING SAME, PROCESSES AND USES | OREAL (FR) | 2018-05-16 | — | — | EP | disclosed |