Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 17/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 14/20 | 0.65 |
| ▸ | CCNK | O75909 | 3/20 | 0.50 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697641 | 0.90 | HCRTR2 (0.66) | HCRTR2HCRTR1 | |
| SCHEMBL20144820 | 0.90 | HCRTR2 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL20145146 | 0.90 | HCRTR2 (0.66) | HCRTR2HCRTR1 | |
| SCHEMBL20144808 | 0.89 | HCRTR1 (0.66) | HCRTR2HCRTR1 | |
| SCHEMBL20145116 | 0.89 | HCRTR1 (0.66) | HCRTR2HCRTR1 | |
| SCHEMBL20144896 | 0.88 | HCRTR1 (0.67) | HCRTR2HCRTR1 | |
| SCHEMBL18697746 | 0.88 | HCRTR1 (0.67) | HCRTR2HCRTR1 | |
| SCHEMBL20144988 | 0.87 | HCRTR1 (0.68) | HCRTR2HCRTR1CCNKCDK12 | |
| SCHEMBL18697535 | 0.87 | HCRTR1 (0.68) | HCRTR2HCRTR1CCNKCDK12 | |
| SCHEMBL20144946 | 0.86 | HCRTR2 (0.67) | HCRTR2HCRTR1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |