Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.69 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.65 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697634 | 1.00 | HCRTR2 (0.69) | HCRTR2HCRTR1PDE2AKMT2AOPRK1 | |
| SCHEMBL20144883 | 0.88 | HCRTR2 (0.68) | HCRTR2HCRTR1PDE2AOPRK1 | |
| SCHEMBL20144764 | 0.84 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL18697644 | 0.84 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL20144958 | 0.82 | HCRTR2 (0.69) | HCRTR2HCRTR1PDE2A | |
| SCHEMBL18697565 | 0.82 | HCRTR2 (0.69) | HCRTR2HCRTR1PDE2A | |
| SCHEMBL16030662 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16031575 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16149261 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16030664 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |