Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 11/20 | 0.69 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697565 | 1.00 | HCRTR2 (0.69) | HCRTR2PDE2AHCRTR1GFEREGFR | |
| SCHEMBL20144883 | 0.84 | HCRTR2 (0.68) | HCRTR2PDE2AHCRTR1GFEREGFR | |
| SCHEMBL20144748 | 0.82 | HCRTR2 (0.69) | HCRTR2PDE2AHCRTR1 | |
| SCHEMBL18697634 | 0.82 | HCRTR2 (0.69) | HCRTR2PDE2AHCRTR1 | |
| SCHEMBL16148117 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16030109 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16030110 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16078138 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16032561 | 0.82 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL20144897 | 0.81 | HCRTR2 (0.68) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |