Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 10/20 | 0.70 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.57 |
| ▸ | CCNK | O75909 | 2/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697778 | 1.00 | HCRTR1 (0.70) | HCRTR1HCRTR2CCNKCDK12GFER | |
| SCHEMBL20144927 | 0.90 | HCRTR1 (0.70) | HCRTR1HCRTR2CCNKCDK12GFER | |
| SCHEMBL20144929 | 0.88 | HCRTR1 (0.72) | HCRTR1HCRTR2CCNKCDK12 | |
| SCHEMBL20144831 | 0.87 | HCRTR1 (0.70) | HCRTR1HCRTR2CCNKCDK12GFER | |
| SCHEMBL20144889 | 0.87 | HCRTR1 (0.70) | HCRTR1HCRTR2CCNKCDK12GFER | |
| SCHEMBL16031557 | 0.83 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL20144844 | 0.81 | HCRTR1 (0.69) | HCRTR1HCRTR2CCNKCDK12GFER | |
| SCHEMBL20144965 | 0.79 | HCRTR1 (0.72) | HCRTR1HCRTR2GFEROPRK1KMT2A | |
| SCHEMBL20144795 | 0.79 | HCRTR1 (0.72) | HCRTR1HCRTR2GFEROPRK1KMT2A | |
| SCHEMBL20144912 | 0.76 | HCRTR1 (0.56) | HCRTR1HCRTR2CCNKCDK12GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |