SCHEMBL201450

SCHEMBL201450

CCCCOc1cccc(C(N)=O)c1

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.62
SMPD1 P17405 3/20 0.61
PLA2G4B P0C869 1/20 0.60
PARP1 P09874 1/20 0.60
THRB P10828 2/20 0.59
NR1H4 Q96RI1 2/20 0.58
PRSS1 P07477 6/20 0.57
TNKS O95271 1/20 0.57
PARP15 Q460N3 1/20 0.57
PARP14 Q460N5 1/20 0.57
PARP10 Q53GL7 1/20 0.57
TNKS2 Q9H2K2 1/20 0.57
PARP2 Q9UGN5 1/20 0.57
THRA P10827 1/20 0.56
KAT6A Q92794 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203104 0.95 SMPD1 (0.68) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL202777 0.94 SMPD1 (0.70) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL202638 0.94 SMPD1 (0.70) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL14421817 0.94 SMPD1 (0.70) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL204298 0.94 SMPD1 (0.70) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL201242 0.94 SMPD1 (0.70) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL12951117 0.94 SMPD1 (0.70) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL201524 0.92 KMT2A (0.73) KMT2ASMPD1PARP1NR1H4PRSS1
SCHEMBL31609710 0.90 PLA2G4B (0.58) KMT2ASMPD1PLA2G4BPARP1THRB
SCHEMBL202778 0.90 PLA2G4B (0.58) KMT2ASMPD1PLA2G4BPARP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1429108-A Phosphate transport inhibitors SMITHKLINE BEECHAM CORP (US) 2003-07-09 CN claimed
JP-H09510704-A 1997-10-28 JP claimed
EP-0749415-A1 BENZAMIDE ANALOGS, USEFUL AS PARP (ADP-RIBOSYLTRANSFERASE, ADPRT) DNA REPAIR ENZYME INHIBITORS NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) 1996-12-27 EP claimed
WO-1995024379-A1 BENZAMIDE ANALOGS, USEFUL AS PARP (ADP-RIBOSYLTRANSFERASE, ADPRT) DNA REPAIR ENZYME INHIBITORS NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) 1995-09-14 WO claimed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
EP-3508484-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2021-04-07 EP disclosed
EP-3342771-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-11-25 EP disclosed
WO-2020212227-A1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL) ETHYLAMINO]ALKANEAMIDE DERIVATIVES NEWRON PHARMACEUTICALS S.P.A. (IT) 2020-10-22 WO disclosed
EP-3375780-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-06-03 EP disclosed
EP-3508484-A1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2019-07-10 EP disclosed
US-10272074-B2 Inhibitors of glucocorticoid receptor translocation Sanford Burnham Prebys Medical Discovery Institute (US) 2019-04-30 US disclosed
US-20180207140-A1 Pyrazolopyrimidines as Inhibitors of Glucocorticoid Receptor Translocation Sanford Burnham Prebys Medical Discovery Institute 2018-07-26 US disclosed
US-5543275-A PYRAZOLO(1,5-B)(1,2,4)TRIAZOLE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5534390-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-07-09 US disclosed
WO-1995024379-A1 BENZAMIDE ANALOGS, USEFUL AS PARP (ADP-RIBOSYLTRANSFERASE, ADPRT) DNA REPAIR ENZYME INHIBITORS NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) 1995-09-14 WO disclosed
US-5223384-A Multilayer; paper support, subbing and photosensitive layer KONICA CORPORATION (JP) 1993-06-29 US disclosed
EP-0256820-B1 THERMAL DEVELOPING LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-07-29 EP disclosed
US-5032499-A High density, stability KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-07-16 US disclosed
EP-0256820-A2 Thermal developing light-sensitive material KONICA CORPORATION (JP) 1988-02-24 EP disclosed
US-4304935-A Production of 1-phenyl-3-cyanoureas REXOLIN CHEMICALS AB (SE) 1981-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180207140-A1 Pyrazolopyrimidines as Inhibitors of Glucocorticoid Receptor Translocation NR3C1, NR3C2, GRK3 KMT2A 3251/4885SMPD1 3149/4885PLA2G4B 2060/4885
US-10272074-B2 Inhibitors of glucocorticoid receptor translocation NR3C1, NR3C2, GRK3 KMT2A 3527/4885SMPD1 2511/4885PLA2G4B 1196/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 KMT2A 1011/4885SMPD1 1055/4885PLA2G4B 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.