Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697566 | 1.00 | HCRTR1 (0.51) | HCRTR1HCRTR2GAAMAPTCYP2C9 | |
| SCHEMBL18697757 | 0.91 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL20144986 | 0.91 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL20145168 | 0.90 | HCRTR1 (0.57) | HCRTR1HCRTR2GAAMAPTCYP2C9 | |
| SCHEMBL20145013 | 0.90 | HCRTR1 (0.57) | HCRTR1HCRTR2GAAMAPTCYP2C9 | |
| SCHEMBL20144918 | 0.90 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL18697740 | 0.89 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL20144871 | 0.89 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL18697848 | 0.84 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL20144950 | 0.84 | HCRTR1 (0.67) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |