Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.56 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | BLVRB | P30043 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555300 | 0.95 | XDH (0.56) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL457516 | 0.95 | XDH (0.56) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL12816887 | 0.94 | XDH (0.55) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL30254454 | 0.90 | XDH (0.70) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL1356995 | 0.90 | XDH (0.70) | XDHTARBP2ABCC4ABCB11PGR | |
| Methylamine SCHEMBL2635514 | 0.88 | XDH (0.67) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL12186979 | 0.87 | CDC7 (0.50) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL9281637 | 0.87 | XDH (0.56) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL12819579 | 0.86 | XDH (0.55) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL1444276 | 0.84 | XDH (0.53) | XDHTARBP2ABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073617-A1 | PROCESSES FOR THE PREPARATION OF FEBUXOSTAT AND SALTS THEREOF | CIPLA LIMITED (IN) | 2011-06-23 | — | — | WO | disclosed |