Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.62 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.62 |
| ▸ | STING1 | Q86WV6 | 15/20 | 0.40 |
| ▸ | IRF3 | Q14653 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011420 | 0.98 | HCRTR1 (0.65) | HCRTR1HCRTR2STING1IRF3OPRM1 | |
| SCHEMBL2014489 | 0.93 | HCRTR1 (0.61) | HCRTR1HCRTR2STING1IRF3SMYD3 | |
| SCHEMBL2054242 | 0.93 | HCRTR1 (0.61) | HCRTR1HCRTR2STING1IRF3SMYD3 | |
| SCHEMBL2013557 | 0.92 | HCRTR1 (0.64) | HCRTR1HCRTR2STING1IRF3OPRM1 | |
| SCHEMBL2012845 | 0.89 | HCRTR1 (0.64) | HCRTR1HCRTR2STING1IRF3SMYD3 | |
| SCHEMBL2053609 | 0.89 | HCRTR1 (0.64) | HCRTR1HCRTR2STING1IRF3SMYD3 | |
| SCHEMBL2016237 | 0.87 | HCRTR1 (0.64) | HCRTR1HCRTR2OPRM1OPRK1 | |
| SCHEMBL2054319 | 0.87 | HCRTR1 (0.64) | HCRTR1HCRTR2OPRM1OPRK1 | |
| SCHEMBL2013858 | 0.83 | HCRTR1 (0.46) | HCRTR1HCRTR2OPRM1OPRK1 | |
| SCHEMBL2013880 | 0.83 | HCRTR1 (0.46) | HCRTR1HCRTR2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |