Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 16/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.49 |
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16679532 | 0.82 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL16679154 | 0.82 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL16679138 | 0.82 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL20145592 | 0.81 | MAPK1 (0.64) | MAPK1ALOX5APFEN1MAP4K4BMPR1B | |
| SCHEMBL16680919 | 0.81 | MAPK1 (0.47) | MAPK1ALOX5APFEN1MAP4K4 | |
| SCHEMBL16679304 | 0.79 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL30964448 | 0.78 | SMYD3 (0.55) | MAP4K4BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3059096 | 0.78 | SMYD3 (0.55) | MAP4K4BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL16680448 | 0.75 | MAPK1 (0.75) | MAPK1 | |
| SCHEMBL16680445 | 0.75 | MAPK1 (0.75) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |