Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA1 | Q15418 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 4/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16036504 | 0.92 | RPS6KA1 (0.37) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL16036503 | 0.92 | RPS6KA1 (0.37) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL19977329 | 0.82 | RPS6KA1 (0.36) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL16077586 | 0.75 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL19582116 | 0.74 | CA2 (0.36) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL28426675 | 0.71 | RPS6KA1 (0.36) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL26334329 | 0.71 | RPS6KA1 (0.41) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL19602653 | 0.71 | MEN1 (0.39) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL19602655 | 0.71 | MEN1 (0.39) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL30345772 | 0.71 | CA12 (0.41) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |