Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.63 |
| ▸ | PPARD | Q03181 | 9/20 | 0.63 |
| ▸ | PPARA | Q07869 | 9/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | FABP4 | P15090 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603409 | 0.87 | PPARG (0.76) | PPARGPPARDPPARAPTPN1TSHR | |
| SCHEMBL12653083 | 0.87 | PPARG (0.76) | PPARGPPARDPPARAPTPN1TSHR | |
| Dodecanoate SCHEMBL31098927 | 0.87 | PPARG (0.76) | PPARGPPARDPPARAPTPN1TSHR | |
| SCHEMBL1603411 | 0.87 | PPARG (0.76) | PPARGPPARDPPARAPTPN1TSHR | |
| Heptanoate SCHEMBL23581067 | 0.86 | PPARG (0.77) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL23928832 | 0.86 | F7 (0.62) | PPARGPPARDPPARAPTPN1TSHR | |
| SCHEMBL23928833 | 0.86 | F7 (0.62) | PPARGPPARDPPARAPTPN1TSHR | |
| SCHEMBL12653086 | 0.86 | F7 (0.62) | PPARGPPARDPPARAPTPN1TSHR | |
| Hexanoate SCHEMBL28221448 | 0.84 | AKR1B1 (0.76) | PPARGPPARDPPARAGPR84HDAC11 | |
| Sebacic Acid SCHEMBL23781711 | 0.79 | GPR84 (1.00) | PPARGPPARDPPARAGPR84HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210169776-A1 | COSMETIC COMPOSITION WITH A METALLIC EFFECT | CHANEL PARFUMS BEAUTE (FR) | 2021-06-10 | — | — | US | disclosed |
| US-20110146702-A1 | EXTENDING COSMETIC COMPOSITION COMPRISING BEHENYL ALCOHOL AS THICKENER | L'OREAL (FR) | 2011-06-23 | — | — | US | disclosed |
| WO-2010146147-A2 | COMPOSITION FOR TREATING KERATIN FIBRES COMPRISING A BLOCK COPOLYMER, A SILOXANE RESIN AND A VOLATILE SOLVENT | L'OREAL (FR) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010125543-A2 | COSMETIC COMPOSITION COMPRISING A SURFACTANT WITH HLB GREATER THAN OR EQUAL TO 12 AND A COATED PIGMENT | L'OREAL (FR) | 2010-11-04 | — | — | WO | disclosed |
| US-4367220-A | COMPOSED OF LIPOSOLUBLE VINYL ESTER POLYMER UNITS, 1-DOCOSANOYLOXY-3-(2-ETHYL)-HEXYLOXY-2-PROPANOL, FAT AND COLORING MATERIAL | L'OREAL (FR) | 1983-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110146702-A1 | EXTENDING COSMETIC COMPOSITION COMPRISING BEHENYL ALCOHOL AS THICKENER | KRT18, PHOSPHO1, DEGS1 | PPARG 998/4885PPARD 943/4885PPARA 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.