SCHEMBL20146550

SCHEMBL20146550

Cc1ccc2c(oc3ccccc32)c1N1C=CN(c2c(C(C)C)cccc2C(C)C)C1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
ALOX15 P16050 1/20 0.33
PGR P06401 1/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
ALOX5 P09917 1/20 0.30
HSD17B10 Q99714 2/20 0.30
HTT P42858 2/20 0.30
MAPK1 P28482 1/20 0.30
MAPT P10636 1/20 0.30
NPY1R P25929 1/20 0.30
NPY2R P49146 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449638 1.00 MEN1 (0.34) MEN1KMT2ACYP2C19ALDH1A1TSHR
SCHEMBL21142404 0.92 MEN1 (0.31) MEN1KMT2ACYP2C19ALDH1A1PGR
SCHEMBL21074287 0.89 MEN1 (0.38) MEN1KMT2ACYP2C19ALDH1A1TSHR
SCHEMBL19999699 0.89 MEN1 (0.38) MEN1KMT2ACYP2C19ALDH1A1TSHR
SCHEMBL25632758 0.88 MAPT (0.32) ALDH1A1MAPTLMNA
SCHEMBL25793932 0.87 CYP2C19 (0.33) MEN1KMT2ACYP2C19ALDH1A1TSHR
SCHEMBL21758899 0.85 MAPK1 (0.32) MEN1KMT2ACYP2C19ALDH1A1TSHR
SCHEMBL24828713 0.85 MEN1 (0.36) MEN1KMT2ACYP2C19ALDH1A1PPARG
SCHEMBL27432087 0.85 MEN1 (0.36) MEN1KMT2ACYP2C19ALDH1A1PPARG
SCHEMBL19224801 0.84 MEN1 (0.35) MEN1KMT2ACYP2C19ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254697-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-22 US disclosed
EP-3789379-A1 4-PHENYLBENZO[G]QUINAZOLINE OR 4-(3,5-DIMETHYLPHENYLBENZO[G]QUINAZOLINE IRIDIUM COMPLEXES FOR USE AS NEAR-INFRARED OR INFRARED EMITTING MATERIALS IN OLEDS Universal Display Corporation (US) 2021-03-10 EP disclosed
US-20210024558-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 US disclosed
EP-3323822-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2019-08-28 EP disclosed
EP-3323822-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-05-23 EP disclosed
EP-3321258-A1 4-PHENYLBENZO[G]QUINAZOLINE OR 4-(3,5-DIMETHYLPHENYLBENZO[G]QUINAZOLINE IRIDIUM COMPLEXES FOR USE AS NEAR-INFRARED OR INFRARED EMITTING MATERIALS IN OLEDS Universal Display Corporation (US) 2018-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11254697-B2 Organic electroluminescent materials and devices LEF1, L1CAM, AP1M1 MEN1 1089/4885KMT2A 1458/4885CYP2C19 3132/4885
US-20210024558-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LEF1, L1CAM, AP1M1 MEN1 1089/4885KMT2A 1458/4885CYP2C19 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.