SCHEMBL20146558

SCHEMBL20146558

Cc1cc2c(I)c(C)c(C)cc2s1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20126954 0.80 ALDH1A1 (0.36) ALDH1A1
SCHEMBL25675331 0.75 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15281129 0.70 ALDH1A1 (0.39) ALDH1A1
SCHEMBL20146542 0.69 KDM4E (0.36) ALDH1A1
SCHEMBL17345875 0.67 HSD17B10 (0.39) ALDH1A1
SCHEMBL11721559 0.66 CYP3A4 (0.33)
SCHEMBL4416724 0.64 ALDH1A1 (0.52) ALDH1A1
SCHEMBL18195359 0.64 ALDH1A1 (0.32) ALDH1A1
SCHEMBL26749938 0.64 GAA (0.33) ALDH1A1
SCHEMBL18800856 0.62 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3321258-A1 4-PHENYLBENZO[G]QUINAZOLINE OR 4-(3,5-DIMETHYLPHENYLBENZO[G]QUINAZOLINE IRIDIUM COMPLEXES FOR USE AS NEAR-INFRARED OR INFRARED EMITTING MATERIALS IN OLEDS Universal Display Corporation (US) 2018-05-16 EP disclosed