Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574597 | 1.00 | HSD17B1 (0.49) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL4366927 | 1.00 | HSD17B1 (0.49) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL13580184 | 1.00 | HSD17B1 (0.49) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL19596545 | 0.98 | HSD17B1 (0.48) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL22640634 | 0.98 | HSD17B1 (0.48) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL19347012 | 0.97 | HSD17B1 (0.47) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL17368987 | 0.96 | HSD17B1 (0.47) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL22422944 | 0.96 | HSD17B1 (0.47) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL2500852 | 0.96 | HSD17B1 (0.47) | HSD17B1HSD17B2MAPTPOLBCTDSP1 | |
| SCHEMBL10065951 | 0.96 | HSD17B1 (0.47) | HSD17B1HSD17B2MAPTPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917198-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-16 | — | — | EP | disclosed |