Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365404 | 1.00 | CTSK (0.45) | CTSKCTSSBCHEACHEPLA2G2C | |
| SCHEMBL15457738 | 0.89 | CTSK (0.51) | CTSKCTSSBCHEACHECYP1A2 | |
| SCHEMBL13983158 | 0.89 | CTSK (0.51) | CTSKCTSSBCHEACHECYP1A2 | |
| SCHEMBL28190852 | 0.89 | CTSK (0.55) | CTSKCTSS | |
| SCHEMBL5623720 | 0.86 | CTSK (0.44) | CTSKCTSSACHE | |
| SCHEMBL4362188 | 0.86 | CTSK (0.44) | CTSKCTSSACHE | |
| SCHEMBL7284821 | 0.85 | BCHE (0.52) | CTSKCTSSBCHEACHEPLA2G2C | |
| SCHEMBL7288988 | 0.85 | BCHE (0.52) | CTSKCTSSBCHEACHEPLA2G2C | |
| SCHEMBL19692119 | 0.85 | CTSK (0.45) | CTSKCTSSACHECYP1A2CYP2C9 | |
| SCHEMBL7006306 | 0.85 | KMT2A (0.49) | PLA2G2CITGB3ITGA2BFOLH1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197885-A2 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | Chao, Yu-Sheng (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048861-A2 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2016-03-31 | — | — | WO | disclosed |
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| EP-1230243-A1 | POYCYLOALKYLPURINES AS ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN, INC. (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034610-A1 | POLYCYCLOALKYLPURINES AS ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN, INC. (US) | 2001-05-17 | — | — | WO | disclosed |