Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.72 |
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148976 | 0.88 | RORC (0.57) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL20149241 | 0.88 | RORC (0.57) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL14495289 | 0.87 | PDE4B (0.58) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL4004826 | 0.87 | PDE4B (0.58) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL1970572 | 0.87 | PDE4B (0.58) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL15397686 | 0.87 | PDE4B (0.58) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL5730196 | 0.87 | PDE4B (0.58) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL1972562 | 0.87 | PDE4B (0.58) | RORCTACR1MEN1KMT2APDE4B | |
| SCHEMBL20148981 | 0.86 | RORC (0.68) | RORCTACR1PDE4BNAMPTUSP30 | |
| SCHEMBL3993928 | 0.86 | RORC (0.55) | RORCTACR1MEN1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |