Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139587 | 0.79 | RORC (0.57) | RORCGBA1MLYCDNR1H3NR1H2 | |
| Hydrochloric Acid SCHEMBL23683624 | 0.78 | RORC (0.56) | RORCGBA1MLYCDNR1H3NR1H2 | |
| SCHEMBL20149260 | 0.65 | RORC (0.54) | RORCMLYCDNR1H3NR1H2 | |
| SCHEMBL20139695 | 0.65 | RORC (0.60) | RORCNR1H2RORA | |
| Hydrochloric Acid SCHEMBL16032992 | 0.63 | GBA1 (0.56) | RORCGBA1 | |
| SCHEMBL20140907 | 0.62 | RORC (0.62) | RORC | |
| SCHEMBL3626633 | 0.62 | NR1H2 (0.39) | RORCMLYCDNR1H3NR1H2RORA | |
| Bromide SCHEMBL7303884 | 0.60 | GBA1 (0.49) | GBA1 | |
| Bromide SCHEMBL7304419 | 0.60 | GBA1 (0.49) | GBA1 | |
| Bromide SCHEMBL7304433 | 0.60 | GBA1 (0.49) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |