Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.68 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713118 | 0.81 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20148961 | 0.81 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20148964 | 0.80 | RORC (0.80) | RORCNR1I2 | |
| Hydrochloric Acid SCHEMBL23683591 | 0.80 | RORC (0.98) | RORCNR1I2 | |
| SCHEMBL20139578 | 0.80 | RORC (0.80) | RORCNR1I2 | |
| SCHEMBL20148962 | 0.79 | RORC (0.91) | RORCNR1I2 | |
| SCHEMBL20149259 | 0.79 | RORC (0.69) | RORCNR1I2 | |
| Trifluoroacetic Acid SCHEMBL20140240 | 0.77 | RORC (0.89) | RORCNR1I2 | |
| Trifluoroacetic Acid SCHEMBL20142131 | 0.77 | RORC (0.89) | RORCNR1I2 | |
| Trifluoroacetic Acid SCHEMBL20140496 | 0.75 | RORC (0.74) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |