Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23712997 | 0.90 | RORC (0.60) | RORC | |
| SCHEMBL20149072 | 0.88 | RORC (0.50) | RORCUSP30 | |
| SCHEMBL20139636 | 0.86 | RORC (0.58) | RORCTACR1 | |
| SCHEMBL23683600 | 0.86 | RORC (0.58) | RORCTACR1 | |
| SCHEMBL20140351 | 0.76 | RORC (0.72) | RORC | |
| SCHEMBL20141079 | 0.76 | RORC (0.72) | RORC | |
| SCHEMBL20139607 | 0.73 | RORC (0.74) | RORC | |
| SCHEMBL20139658 | 0.73 | RORC (0.74) | RORC | |
| SCHEMBL23683608 | 0.72 | RORC (0.58) | RORCUSP30 | |
| SCHEMBL20139710 | 0.72 | RORC (0.58) | RORCUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |