Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149055 | 0.71 | RORC (0.56) | RORCNR1I2 | |
| SCHEMBL20149102 | 0.67 | RORC (0.68) | RORCNR1I2 | |
| SCHEMBL20149260 | 0.67 | RORC (0.54) | RORCNR1H3MLYCDNR1I2 | |
| SCHEMBL23713056 | 0.66 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL15113836 | 0.65 | KCNQ3 (0.61) | — | |
| Bicarbonate SCHEMBL7569185 | 0.65 | MEN1 (0.57) | — | |
| SCHEMBL20149112 | 0.64 | RORC (1.00) | RORC | |
| SCHEMBL20149585 | 0.64 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL23713002 | 0.64 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20149087 | 0.64 | RORC (0.75) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |