SCHEMBL2014916

SCHEMBL2014916

C=C(CC(=O)Oc1ccccc1)C(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.45
ELANE P08246 2/20 0.44
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
HSD17B10 Q99714 3/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX15 P16050 2/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.37
RAD51 Q06609 1/20 0.37
LGALS8 O00214 1/20 0.36
EGFR P00533 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685329 0.89 ALDH1A1 (0.46) CYP19A1ELANEALDH1A1MAPTHSD17B10
SCHEMBL528298 0.87 CYP19A1 (0.46) CYP19A1ELANEALDH1A1MAPTHSD17B10
SCHEMBL528297 0.87 ELANE (0.45) CYP19A1ELANEALDH1A1MAPTHSD17B10
SCHEMBL6517377 0.86 CYP19A1 (0.41) CYP19A1ELANEALDH1A1MAPTHSD17B10
SCHEMBL28949409 0.85 ALDH1A1 (0.46) ELANEALDH1A1MAPTHSD17B10KMT2A
SCHEMBL9355846 0.84 ALDH1A1 (0.47) CYP19A1ALDH1A1MAPTKMT2ALMNA
SCHEMBL27494888 0.84 ALDH1A1 (0.47) CYP19A1ELANEALDH1A1MAPTHSD17B10
SCHEMBL11710172 0.84 ELANE (0.42) CYP19A1ELANEALDH1A1MAPTHSD17B10
SCHEMBL689834 0.84 KMT2A (0.43) ELANEALDH1A1MAPTHSD17B10KMT2A
SCHEMBL6515808 0.82 KMT2A (0.44) CYP19A1ELANEALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010891-A1 ADHESIVE TWO-COMPONENT COMPOSITION BASED ON ITACONATE MONOMER BOSTIK SA (FR) 2024-01-11 US claimed
EP-4255945-A1 ADHESIVE TWO-COMPONENT COMPOSITION BASED ON ITACONATE MONOMER Bostik SA (FR) 2023-10-11 EP claimed
CN-116472297-A Two-component adhesive compositions based on itaconate monomers 博斯蒂克股份公司 2023-07-21 CN claimed
WO-2022117940-A1 ADHESIVE TWO-COMPONENT COMPOSITION BASED ON ITACONATE MONOMER BOSTIK SA (FR) 2022-06-09 WO claimed
WO-2011085445-A1 FLOTATION REAGENTS TEEBEE HOLDINGS PTY LTD (AU) 2011-07-21 WO claimed
US-5563290-A Method for preparing optically active succinic acid compound NIPPON OIL CO. LTD. (JP) 1996-10-08 US claimed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-5093447-A Contact lenses NOVICKY NICK N (CA) 1992-03-03 US claimed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US claimed
US-4861850-A CONTACT LENSES PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) 1989-08-29 US claimed
US-4748224-A Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof Devou, Maureen J. (CA) 1988-05-31 US claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
EP-0231572-A2 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RESEARCH LTD. (CA) 1987-08-12 EP claimed
EP-0067254-A1 Oxygen permeable hard and semi-hard contact lens compositions, processes for their preparation, contact lenses and their manufacture from such compositions SYNTEX (U.S.A.) INC. (US) 1982-12-22 EP claimed
US-4248989-A MACHINABLE, DIMENSIONALLY STABLE SYNTEX OPHTHALMICS, INC., 1981-02-03 US claimed
US-4152508-A OXYGEN PERMEABILITY, DIMENSIONAL STABILITY POLYMER TECHNOLOGY CORPORATION (US) 1979-05-01 US claimed
US-12479947-B2 Curable compositions useful for obtaining non-sensitizing cured products ARKEMA FRANCE (FR) 2025-11-25 US disclosed
US-12466907-B2 Acrylic rubber composition and rubber crosslinked product ZEON CORPORATION (JP) 2025-11-11 US disclosed
US-4018744-A Storage stable polyester-polyurethane-producing compositions ATLANTIC RICHFIELD COMPANY (US) 1977-04-19 US disclosed
US-3950285-A PREPARATION OF POLYMERIC URETHANES FROM DICARBAMATES ATLANTIC RICHFIELD COMPANY (US) 1976-04-13 US disclosed