Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599131 | 0.81 | SLC2A1 (0.39) | MCHR1SLC2A1DHODH | |
| SCHEMBL14453810 | 0.81 | TLR8 (0.36) | MCHR1 | |
| SCHEMBL29568555 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL22804322 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL3255484 | 0.73 | MAPT (0.47) | — | |
| SCHEMBL26814553 | 0.71 | KDM4E (0.44) | DHODH | |
| SCHEMBL12329319 | 0.71 | HTT (0.37) | MCHR1DHODH | |
| SCHEMBL171317 | 0.71 | MRGPRX4 (0.38) | MCHR1SLC2A1DHODH | |
| SCHEMBL2784570 | 0.70 | MAPT (0.49) | MCHR1 | |
| SCHEMBL28784596 | 0.70 | CYP4F2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089373-A9 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018089373-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |