SCHEMBL20149557

SCHEMBL20149557

CCCCCCCCCC(=O)OCCCCCCCN(CCCCCCCOC(=O)CCCCCCCCC)CCOC(=O)CCCN(C)C

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.72
DGKA P23743 1/20 0.56
NAAA Q02083 1/20 0.51
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
HTR2C P28335 1/20 0.47
FAAH O00519 1/20 0.44
PAM P19021 2/20 0.44
THRA P10827 2/20 0.43
THRB P10828 2/20 0.43
TSHR P16473 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15026965 0.96 DNM1 (0.73) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL25761527 0.94 DNM1 (0.71) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL8442490 0.93 DNM1 (0.79) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL5179416 0.93 DNM1 (0.79) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL5178920 0.93 DNM1 (0.79) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL7035299 0.93 DNM1 (0.79) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL20149658 0.92 DNM1 (0.64) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL25125901 0.91 DNM1 (0.71) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL17367539 0.91 DNM1 (0.71) DNM1DGKANAAAPRSS1PRSS2
SCHEMBL17367563 0.91 DNM1 (0.71) DNM1DGKANAAAPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2025-05-22 US claimed
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-12-26 US claimed
EP-3538515-B1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2022-07-20 EP claimed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US claimed
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2025-05-22 US disclosed
US-20240246898-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-07-25 US disclosed
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-12-26 US disclosed
EP-3538515-B1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2022-07-20 EP disclosed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US disclosed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US disclosed
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof NPC1L1, NPC1, CETP DNM1 165/4885DGKA 602/4885NAAA 593/4885
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP DNM1 165/4885DGKA 602/4885NAAA 593/4885
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP DNM1 165/4885DGKA 602/4885NAAA 593/4885
US-20240246898-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP DNM1 165/4885DGKA 602/4885NAAA 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.