Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395931 | 1.00 | SLC6A4 (0.55) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Hydrochloric Acid SCHEMBL18395437 | 0.99 | SLC6A4 (0.56) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Phosphoric Acid SCHEMBL18396245 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Sulfuric Acid SCHEMBL18395716 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Sulfuric Acid SCHEMBL18395715 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Phosphoric Acid SCHEMBL30025576 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Sulfuric Acid SCHEMBL30025453 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Sulfuric Acid SCHEMBL22393227 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| Sulfuric Acid SCHEMBL22393226 | 0.96 | SLC6A4 (0.51) | SLC6A4ALDH1A1MAPTRECQLARG1 | |
| SCHEMBL23668053 | 0.95 | SLC6A4 (0.50) | SLC6A4ALDH1A1MAPTRECQLARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004167-B | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-111004167-A | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2020-04-14 | — | — | CN | disclosed |
| EP-3613420-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | Newlink Genetics Corporation (US) | 2020-02-26 | — | — | EP | disclosed |
| US-10207990-B2 | Salts and prodrugs of 1-methyl-D-tryptophan | NEWLINK GENETICS CORPORATION (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180134658-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA, INC. | 2018-05-17 | — | — | US | disclosed |
| US-20180134658-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10207990-B2 | Salts and prodrugs of 1-methyl-D-tryptophan | IDO1, IDO2, INMT | SLC6A4 21/4885ALDH1A1 634/4885MAPT 2135/4885 |
| US-20180134658-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | IDO1, IDO2, INMT | SLC6A4 21/4885ALDH1A1 634/4885MAPT 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.