Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 8/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149780 | 0.89 | MTOR (0.48) | MTORRPTORMLST8ALDH1A1GRM5 | |
| SCHEMBL20129669 | 0.87 | MTOR (0.48) | MTORRPTORMLST8ALDH1A1GRM5 | |
| SCHEMBL20129667 | 0.85 | KDM4E (0.41) | MTORRPTORMLST8ALDH1A1GRM5 | |
| SCHEMBL20129670 | 0.82 | MTOR (0.41) | MTORRPTORMLST8ALDH1A1DRD2 | |
| SCHEMBL20140972 | 0.81 | MTOR (0.56) | MTORRPTORMLST8ALDH1A1GRM5 | |
| SCHEMBL22693221 | 0.79 | MTOR (0.45) | MTORRPTORMLST8ALDH1A1GRM5 | |
| SCHEMBL20149883 | 0.77 | MTOR (0.45) | MTORRPTORMLST8ALDH1A1GRM5 | |
| SCHEMBL20129674 | 0.77 | MTOR (0.51) | MTORRPTORMLST8GRM5DRD2 | |
| SCHEMBL20129636 | 0.76 | MTOR (0.49) | MTORRPTORMLST8GRM5DRD2 | |
| SCHEMBL20129662 | 0.76 | MTOR (0.49) | MTORRPTORMLST8GRM5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |