Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.68 |
| ▸ | RPTOR | Q8N122 | 9/20 | 0.68 |
| ▸ | MLST8 | Q9BVC4 | 9/20 | 0.68 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133544 | 0.88 | MTOR (0.63) | MTORRPTORMLST8PARP1GRM5 | |
| SCHEMBL20141518 | 0.88 | MTOR (0.63) | MTORRPTORMLST8PARP1GRM5 | |
| SCHEMBL20149921 | 0.86 | MTOR (0.65) | MTORRPTORMLST8GRM5DPP4 | |
| SCHEMBL20133719 | 0.85 | MTOR (0.73) | MTORRPTORMLST8DPP4DRD4 | |
| SCHEMBL21360301 | 0.84 | MTOR (0.78) | MTORRPTORMLST8GRM5DRD4 | |
| SCHEMBL22693235 | 0.82 | MTOR (0.63) | MTORRPTORMLST8DPP4DRD4 | |
| SCHEMBL20133578 | 0.82 | MTOR (0.65) | MTORRPTORMLST8GRM5DRD4 | |
| SCHEMBL21340102 | 0.81 | MTOR (0.84) | MTORRPTORMLST8GRM5DPP4 | |
| SCHEMBL20141028 | 0.81 | MTOR (0.64) | MTORRPTORMLST8GRM5DRD4 | |
| Hydrochloric Acid SCHEMBL20141401 | 0.81 | MTOR (0.64) | MTORRPTORMLST8GRM5DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |