Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 7/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | SI | P14410 | 7/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 5/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150834 | 0.87 | ASAH1 (0.60) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL25758677 | 0.86 | ASAH1 (0.67) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL20150832 | 0.79 | ASAH1 (0.71) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL25504900 | 0.76 | ASAH1 (0.70) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL8221643 | 0.75 | ASAH1 (0.64) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL17875212 | 0.74 | ASAH1 (0.59) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL8221504 | 0.74 | ASAH1 (0.60) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL427517 | 0.74 | ASAH1 (0.70) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL13875221 | 0.73 | ASAH1 (1.00) | ASAH1MGLLMGAMAMY1AGAA | |
| SCHEMBL12593869 | 0.73 | ASAH1 (0.58) | ASAH1MGLLMGAMAMY1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134871-A1 | ADDITION-CURABLE SILICONE RUBBER COMPOSITION AND CURED PRODUCT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134871-A1 | ADDITION-CURABLE SILICONE RUBBER COMPOSITION AND CURED PRODUCT | TST, SUGT1, RAD51 | ASAH1 4108/4885MGLL 2882/4885MGAM 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.