SCHEMBL20152137

SCHEMBL20152137

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5c6c7ccccc7n(-c7nc(-c8ccccc8)nc(-c8cccc(-c9ccccc9)c8)n7)c6ccc54)n3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GP6 Q9HCN6 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ABCG2 Q9UNQ0 3/20 0.34
ABCB1 P08183 1/20 0.34
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20226315 0.95 GP6 (0.33) GP6L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL23118604 0.95 KDM4E (0.42) L3MBTL1MEN1KMT2AABCG2ATM
SCHEMBL19769802 0.95 KDM4E (0.42) L3MBTL1MEN1KMT2AABCG2ATM
SCHEMBL20226362 0.95 GP6 (0.33) GP6L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL20226361 0.94 MEN1 (0.33) GP6L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL23600345 0.94 KDM4E (0.38) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL23598394 0.94 KDM4E (0.38) L3MBTL1MEN1KMT2AABCG2ATM
SCHEMBL20149419 0.94 KDM4E (0.38) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL23118605 0.94 KDM4E (0.41) L3MBTL1MEN1KMT2AABCG2ATM
SCHEMBL19769806 0.94 KDM4E (0.41) L3MBTL1MEN1KMT2AABCG2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 GP6 4511/4885L3MBTL1 2317/4885MEN1 4244/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 GP6 4511/4885L3MBTL1 2317/4885MEN1 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.