Sugi Predict

Sugi Predict / Compounds / SCHEMBL20152246

SCHEMBL20152246

SCHEMBL20152246

CC(C)c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4cc(-c6ccc7c(c6)c6ccccc6n7-c6ccc(C(C)C)cc6)ccc4n5-c4ccc(C(C)C)cc4)ccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ PTPN1 P18031 2/20 0.40
▸ TNKS O95271 1/20 0.38
▸ PARP1 P09874 1/20 0.38
▸ TNKS2 Q9H2K2 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ PARP2 Q9UGN5 1/20 0.38
▸ RORA P35398 1/20 0.37
▸ RORC P51449 1/20 0.37
▸ RORB Q92753 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ TSPO P30536 1/20 0.36
▸ HDAC4 P56524 1/20 0.36
▸ DHODH Q02127 2/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ PDE10A Q9Y233 1/20 0.35
▸ RAC2 P15153 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17228087 1.00 KDM4E (0.47) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL14649224 0.97 KDM4E (0.44) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL9916243 0.94 KDM4E (0.53) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL9916264 0.94 KDM4E (0.53) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL9916256 0.94 KDM4E (0.53) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL9916254 0.94 KDM4E (0.53) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL262488 0.92 KDM4E (0.44) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL262453 0.92 KDM4E (0.44) KDM4EATML3MBTL1PTPN1TNKS
SCHEMBL21249247 0.91 KDM4E (0.53) KDM4EATML3MBTL1PTPN1RORA
SCHEMBL12376511 0.91 KDM4E (0.47) KDM4EATML3MBTL1PTPN1TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210083202-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-18 — — US disclosed
US-10897016-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-19 — — US disclosed
US-20180138425-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-17 — — US disclosed
US-20180138425-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138425-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, OCIAD1, OCIAD2 KDM4E 1178/4885ATM 4294/4885L3MBTL1 430/4885
US-10897016-B2 Organic electroluminescent materials and devices DDT, OCIAD1, OCIAD2 KDM4E 1178/4885ATM 4294/4885L3MBTL1 430/4885
US-20210083202-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, OCIAD1, OCIAD2 KDM4E 1178/4885ATM 4294/4885L3MBTL1 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.