Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | RAC2 | P15153 | 1/20 | 0.35 |
| ▸ | RAC3 | P60763 | 1/20 | 0.35 |
| ▸ | CDC42 | P60953 | 1/20 | 0.35 |
| ▸ | RAC1 | P63000 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21249247 | 0.91 | KDM4E (0.53) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL20152246 | 0.91 | KDM4E (0.47) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL17228087 | 0.91 | KDM4E (0.47) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL1102407 | 0.90 | KDM4E (0.60) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL9916266 | 0.90 | KDM4E (0.53) | KDM4EL3MBTL1ATMPTPN1HDAC4 | |
| SCHEMBL262641 | 0.89 | KDM4E (0.41) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL262810 | 0.89 | KDM4E (0.41) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL22260172 | 0.89 | KDM4E (0.55) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL9916264 | 0.88 | KDM4E (0.53) | KDM4EL3MBTL1ATMRORARORC | |
| SCHEMBL17228761 | 0.88 | RXRA (0.43) | KDM4EL3MBTL1ATMRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073065-A1 | TRIPLET QUENCHER | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-04-14 | — | — | WO | disclosed |
| US-20110196104-A1 | Norbornene-based copolymers with iridium complexes and exiton transport groups in their side-chains and use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-08-11 | — | — | US | disclosed |